Ion shift in experimental hypertension.

Rabbits weighing from 2000 to 2500g were divided into the following groups: Group Ncontrol animals. Group D-animals with blood pressure elevated in metacorticoid hypertension elicited by the administration of desoxycorticosterone acetate and sodium chloride. Group Eanimals with blood pressure elevated by repeated doses of Ephedrinum basicum solutio oleosa (100mg/kg) every 2nd day during 2 weeks. Group R-rabbits with renal hypertension following unilateral nephrectomy and a partial renal artery ligation. Group Na-animals receiving daily 2.5ml/kg of 3% NaCI solution hypodermically during 6 weeks. Group K-animals receiving analogical amounts of 3% KCI solution. The sodium and potassium concentrations in samples of thoracic aorta, blood plasma and erythrocytes were determined with the use of a flame photometer (Cort and Fencl, 1957).